Scientific publications
Desire Paul D Dzeufiet
Andrea Rosanoff
P Haddad
Léonard Tedong
PD Chuisseu
SD Sockeng FM Kanmangne
International Journal of Complementary & Alternative Medicine
Cashew, Anacardium occidentale Linn of the family Anacardiaceae, has been documented as traditional plant treatment for diabetes and hypertension. 2] In the present study, using antioxidant activity-guided fractionation (DPPH advanced glycation endproducts (AGEs) essays), four extracts (E1 to E4) of A. occidentale leaves were studied for possible antioxidant capacities and vascular activity. We also compared the protective effects of cashew leaf extracts against high glucose mediated toxicity in cultured bovine aortic endothelial cells (EAhy 926 cells). Total antioxidant activity of the extracts of A. occidentale and identified compounds was determined using DPPH free radical scavenging assay. Two extracts of cashew's leaves, E3 and E4, were found to possess significant DPPH radical-scavenging activity with equivalent trolox values of 2188 and 7603 mg trolox/g dried extract, respectively. The order of the radical scavenging potency is E4>E3>E2>E1.
