Publications scientifiques
2017Article de revueanglaisAccès ouvert
Vérification de la session…
Publications scientifiques
Christophe Mezui
Tchinda Fokoua Serges Herve
Amang André Perfusion
Malepa Meda Ginette Blanche
Journal of Medicinal Plants Studies
To avoid the adverse effects (ulcerogenic activity for exemple) of nonsteroidal anti-inflammatory drugs (NSAIDs) while curing pain, some people use medicinal plants. This study investigated the analgesic and non-ulcerogenic activities of the aqueous extract of dried ground aerial parts of Eremomastax speciosa Hochst (Acanthaceae) in mice. The analgesic action was assayed in two experimental models: acetic acid and formalin; and the non-ulcerogenic activity by the observation of the gastric mucosa five hours after administration of different treatments. The aqueous extract of Eremomastax speciosa dose-dependently reduced the number of abdominal contractions induced by intraperitoneal injection of acetic acid, with inhibition percentages of 12.13%, 44.74% and 91.40% respectively for doses 100mg/kg, 200mg/kg (p