Publications scientifiques
Kamini G. Melanie Flore
Charles Félix Bilong Bilong
Iris Bruchhau
TSpace (University of Toronto)
Fifty five medicinal plants belonging to different families selected on \nthe basis of their traditional use against jaundice and various liver \ndisorders were tested for their amoebicidal activities. They were \nextracted and tested for their antiamoebic activity in vitro using \npolyxenic culture of Entamoebic histolytica . As the result, 14 \nexhibited an antiamoebic activity at a dose of 100μg/ml from the \nsecond to the fourth day of incubation. The 14 extracts selected \nextracts were additionnaly tested for 6 days at 10, 100 and \n500μg/ml of concentration, and only the leaves extract of Codiaeum \nvariegatum exhibited a clear antiamoebic activity (EC50=10,74 \nthe second day), and had a more pronounced activity than metronidazole \nthe reference product.
