Publications scientifiques
Autres affiliations : University of Siegen
Anne‐Claire Mitaine‐Offer
Autres affiliations : University of Siegen
Tomofumi Miyamoto
Autres affiliations : University of Siegen
Thomas Paululat
Autres affiliations : University of Siegen
Jean-François Mirjolet
Autres affiliations : University of Siegen
Olivier Duchamp
Autres affiliations : University of Siegen
Dieudonné Emmanuel Pegnyemb
Autres affiliations : University of Siegen
Marie‐Aleth Lacaille‐Dubois* (Auteur correspondant)
Autres affiliations : University of Siegen
Journal of Natural Products
Two new oleanane-type saponins, coriariosides A (1) and B (2), along with a known saponin, gummiferaoside C (3), were isolated from the roots of Albizia coriaria. Their structures were established by extensive analysis of 1D and 2D NMR experiments (COSY, ROESY, TOCSY, HSQC, and HMBC) and mass spectrometry. Compounds 1 and 3 when tested for cytotoxicity against two colorectal human cancer cells showed activity against the HCT 116 (IC50 4.2 microM for 1 and 2.7 microM for 3) and HT-29 (IC50 6.7 microM for 1 and 7.9 microM for 3) cell lines.
