Scientific publications
2004Journal articleEnglish
Trypanocidal activity of bergenin, the major constituent of Flueggea virosa, on Trypanosoma brucei. (opens in a new tab)
Authors
University of Yaoundé I
Other authors
Justin Komguep Nono
Scientific publications
Justin Komguep Nono
Bonaventure Sonké
Colette Denier
Catherine Fontaine
PubMed
The presence of bergenin in substantial amounts in the methanol leaves extract of Flueggea virosa (Euphorbiaceae) was established as a strong chemotaxomic point of differentiation between Flueggea virosa and Securinega virosa. Bergenin showed an inhibitory effect on the growth of the bloodstream form of Trypanosoma brucei with an IC50 value of 1 microM.