Scientific publications
2016Journal articleEnglish
Effects of aqueous root extract of Carpolobia alba G. Don on sexual behaviour in adult male rats (opens in a new tab)
Authors
University of Yaoundé I
Judith Domkam
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Scientific publications
Judith Domkam
Hubert Kenmogne
B. Koloko
Cyprien Magloire Hambe
Marie Ngaha Njila
Emma F. Bend
P. Oundoum Oundoum
Dieudonné Massoma Lembè* (Corresponding author)
Andrologia
Several lines say that a number of natural products, mostly plant based, have been claimed to cure male sexual dysfunction. One of such botanicals is Carpolobia alba G. Don which is used in Cameroon to treat erectile dysfunction and related male sexual debilities. However, the traditional claim has not been scientifically tested. Thirty adult male rats (five groups of six animals) were orally treated daily with distilled water, sildenafil citrate (positive control), 75, 150, 300 mg/kg of C. alba G. Don roots aqueous extract. The erection and ejaculation properties were recorded on the first, seventh and fourteenth day of treatment by following copulation settings: number of erections (NE), mount frequency (MF), intromission frequency (IF), ejaculation frequency (EF), mount latency (ML), intromission latency (IL), ejaculation latency (EL), average interval of copulation (AIC) and post-ejaculatory interval (PEI). The extract resulted in an improvement of copulation parameters through significant reduction (p < .001) of PEI, ML and IL and significant increase (p < .001) in the NE, MF, IF, EF, EL and AIC. These results indicate a pro-erectile and pro-ejaculatory potential of aqueous root extract of this plant in male rats.