Scientific publications
Brice Mittérant Mba’ning
Bruno Ndjakou Lenta
Etienne Tsamo
Flaure Rosette Ehawa Essoung* (Corresponding author)
Other affiliations: International Centre of Insect Physiology and Ecology · University of Ngaoundéré
S.C. Chhabra
Ahmed Hassanali
Alain Tadjong Tcho
Samira A. Mohamed
Silvère Augustin Ngouela
Russell J. Cox
Natural Product Research
Methanolic extracts of liana of Caesalpinia welwitschiana and leaves of C. bonduc were found to possess moderate antifeedant and ovicidal activities against Tuta absoluta. Bioassay-guided isolation of constituents from the most active fraction of C. welwitschiana led to the identification of four known compounds [isobonducellin 1a and bonducellin 1 b, intricatinol 2, (-)-epigallocatechin-3-O-gallate 4] and one new constituent [welwitschianic acid 3]. The most active fraction of C. bonduc afforded two known constituents neocaesalpin L 5 and neocaesalpin A 6. The isolated structures were elucidated on the basis of their MS, UV, IR and 1 & 2 D NMR spectra and by comparison with literature data. Compounds 2, 4-6 were showed antifeedant and ovicidal properties against T. absoluta, some comparable to that of azadirachtin at 50, 100 and 200 ng/µl. Overall, the present study, conclude that the two species of the plant could be a promising source of eco-friendly botanical constituents.
