Scientific publications
David Dako Chiozem
Céline Mbazoa Djama
Véronique Simone Fannang
Hanh Trinh‐Van‐Dufat
Other affiliations: Centre National de la Recherche Scientifique · Université Paris Cité · Chimie Organique, Médicinale et Extractive et Toxicologie Expérimentale
François Tillequin
Other affiliations: Centre National de la Recherche Scientifique · Université Paris Cité · Chimie Organique, Médicinale et Extractive et Toxicologie Expérimentale
Jean Duplex Wansi
Elisabeth Seguin
Chemical and Pharmaceutical Bulletin
Two new friedelane-type triterpenes named 12alpha-hydroxyfriedelane-3,15-dione and 3beta-hydroxyfriedelan-25-al, together with six known compounds were isolated from the stems of Drypetes paxii Hutch. (Euphorbiaceae). Their structures were established on the basis of conventional 1 dimensional (1D) NMR methods, 2D shift-correlated NMR experiments and mass spectra. The five friedelane-type triterpene derivatives and one olean-12-ene triterpene saponin were tested for antimicrobial activity against some gram-positive and gram-negative bacteria, and they appeared to be modestly active.
