Scientific publications
Ferdinand Tantangmo
Other affiliations: Laboratoire de Chémo-biologie synthétique et thérapeutique · Laboratoire d'Innovation Thérapeutique · Université de Strasbourg
Bruno Ndjakou Lenta
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Louis Kamdem
Etienne Tsamo* (Corresponding author)
Bernard Weniger
Other affiliations: Laboratoire d'Innovation Thérapeutique · Université de Strasbourg
Annelise Lobstein
Other affiliations: Laboratoire d'Innovation Thérapeutique · Université de Strasbourg
Catherine Vonthron‐Sénécheau
Other affiliations: Laboratoire d'Innovation Thérapeutique · Université de Strasbourg
Helvetica Chimica Acta
Abstract Phytochemical investigation of the bark and leaves of Pancovia laurentii (Sapindaceae) resulted in the isolation of a new ceramide and a new cerebroside, named pancoviamide ( 1 ), and pancovioside ( 2 ) respectively, together with six known compounds: uracil, ( R )‐ N ‐[(1 S ,2 S ,3 R )‐2,3‐dihydroxy‐1‐(hydroxymethyl)heptadec‐5‐en‐1‐yl]‐2‐hydroxytetracosanamide, stigmasta‐7,22‐dien‐3‐ol, β ‐stitosterol, β ‐sitosterol 3‐ O‐β ‐ D ‐glucopyranoside, and 2,3‐dihydroxypropyl pentadecanoate. The structures of 1 and 2 were determined by means of spectroscopic methods. Compounds 1 and 2 were tested in vitro for their antiprotozoal properties against several protozoa and for their cytotoxicity.
