Scientific publications
2011Journal articleEnglish
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Scientific publications
Benedicta N. Nkeh-Chungag
Emmanuel Yankep
Erick Marcel Noudji
Jacques Djapou
Armel Camille Guimfack Kentsop
Jean Claude Mbanya
AFRICAN JOURNAL OF BIOTECHNOLOGY
Bridelia grandis is used in most parts of tropical Africa for the treatment of diabetes. The anti-diabetic properties of the methanolic stem bark extract of this plant was studied in ob/ob and db/db mice. The plant extract induced hypoglycaemic effects of long duration in the ob/ob mice, while its effects were less pronounced in the db/db mice. Twenty four hours after the cessation of drug administration, both ob/ob and db/db extract treated animals still had significantly lower fasting blood sugar levels when compared to controls, thus confirming its antidiabetic properties.