Scientific publications
Zemo Gamo Franklin
Other affiliations: University of Douala · Wisconsin Academy of Sciences, Arts & Letters
Ateba Sylvin Benjamin
Other affiliations: University of Douala · Wisconsin Academy of Sciences, Arts & Letters
Other affiliations: University of Douala · Wisconsin Academy of Sciences, Arts & Letters
Other affiliations: University of Douala · Wisconsin Academy of Sciences, Arts & Letters
Ketcha Wanda Germain Jean Magloire
International Journal of Engineering Applied Sciences and Technology
Pachystela brevipes (Bak.) Engl (Sapotaceae) is a plant used in West region of Cameroon to improve conception and alleviate vaginal dryness in elderly women. Thus, this study was designed to evaluate the potential estrogenic of the decoction of stem bark of P. brevipes (175, 350 and 700 mg/kg BW) using a 3-day uterotrophic assay in ovariectomized rats. P. brevipes extract had no effect uterine wet weight while, significantly (p < 0.05) increased uterine (at 350 and 700 mg/kg) and vaginal (at 700 mg/kg) epithelial thickness. Moreover, this extract induced an E2V-like effect on mammary gland by increased the diameter of alveoli and induced eosinophil secretion at all tested doses. These results suggest that P. brevipes extract is endowed with estrogenic properties and could justify its traditional used.
