Scientific publications
2012Journal articleEnglishOpen access
Chemical Constituents from Stem Bark and Roots of Clausena anisata (opens in a new tab)
Authors
University of Yaoundé I
Dalhousie University
Jules Lobe Songue
Scientific publications
Jules Lobe Songue
Other affiliations: University of Douala
Robert L. White
Kouam
Théophile Ngando Mpondo
Molecules
Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).