Scientific publications
Ernestine Nkwengoua
Igor Ngantchou
* (Corresponding author)
Colette Denier
Casimir Blonski
Bernd Schneider
Other affiliations: Max Planck Institute for Chemical Ecology
Natural Product Research
In an attempt to establish the components responsible for the use of Enantia chlorantha against cutaneous leishmaniasis in local traditional medicine, a well-known palmatine has been isolated in substantial amounts from a methanolic bark extract of this plant species. Palmatine therein obtained exhibited a significant inhibitory activity on growth of both Trypanosoma cruzi (IC(50) 0.068 microM) and Leishmania infantum (IC(50) 0.79 microM).
