Scientific publications
Julio Issah Mawouma Pagna
Paul Etoga Mbarga
Ines Michèle Kanko Mbekou
* (Corresponding author)
Bruno Ndjakou Lenta
Ephrem Augustin Nkengfack
Tengu Awazi
Fekam Boyom Fabrice
Jean Fotie
Marcel Frese
Norbert Sewald
Journal of Asian Natural Products Research
As part of our search for new secondary metabolites from Macaranga hurifolia Beille, a phytochemical investigation was carried out on the fruits that led to the isolation and characterization of two new prenylated flavonol derivatives named macafolias A (1) and B (2), along with five known compounds. Their chemical structures were established on the basis of extensive analysis of their 1–D and 2–D NMR (1H, 13C, APT, COSY, HSQC and HMBC) in conjunction with mass spectroscopy and by comparison with data from the literature. The in vitro assay of the antibacterial potency of the crude extract, fractions and some pure compounds were evaluated against a wide range of bacteria strains.
