Scientific publications
2022Journal articleEnglishOpen access
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Scientific publications
Minoue Kuum Marc Germain
Tchadji Jules Colince
Christophe Mezui
Journal of Pharmacognosy and Phytochemistry
The present research was carried out to evaluate the effects of Albizia ferruginea aqueous stem bark extract (AFASBE) on the variation of some pro-inflammatory cytokines and haematological parameters during sub-chronic inflammation. Sub-chronic inflammation was induced in rats by the insertion of cotton pellets and then treated with AFASBE. Determination of the concentrations of TNF-α, IL1-β, IL-6 and INF-γ was carried out by the ELISA technique “Enzyme Linked Immuno Sorbent Assay” using the Quantikines kits (France). Haematological parameters were quantified using the Coulter S-Plus IV/D. The levels of TNF-α, IL-1β, IL-6 and INF-γ significantly (p